Weddle is a surname. Notable people with the surname include:
Chris Weddle (born 1983), bodhrán player and instructor David Weddle, American television producer and writer Eric Weddle (born 1985), American football player Jack Weddle (1905–1979), English footballer James D. Weddle, American businessman Mary Weddle (1934–2021), All-American Girls Professional Baseball League player Mat Weddle or Obadiah Parker (born 1983), American singer-songwriter Thomas Weddle (1817–1853) English mathematician Vernon Weddle (born 1935), American film, stage and television actor
See also Weddell (disambiguation), which includes a list of people with the surname