Queen of the South may refer to:

People Queen of the South (biblical reference), an alternative title for the Queen of Sheba used in the New Testament "Queen of the South", a nickname for Kyrgyzstani stateswoman Kurmanjan Datka

Places The nickname for the town of Dumfries, Scotland

Arts, entertainment, and media The Queen of the South (novel), the English title of La Reina del Sur, a 2002 Spanish novel by Arturo Pérez-Reverte La Reina del Sur (telenovela), a 2011 Spanish-language telenovela produced by the United States-based television network Telemundo based on the novel Queen of the South (TV series), an American television series adaptation of the telenovela "Queen of the South", a song by the Scottish record producer Bill Drummond on the 1986 album The Man "Queen of the South", a song on the 1993 album Liberation by The Divine Comedy

Sports Queen of the South F.C., a Scottish professional football club in Dumfries Queen of the South Stakes, a South Australian Jockey Club horse race

See also Queen City of the South, a moniker for Cebu City, Philippines