Vaughan House may refer to:
Vaughan House, Adelaide, historic "home for wayward girls" in Adelaide, South Australia Vaughan House (Little Rock, Arkansas), listed on the NRHP in Little Rock, Arkansas
See also John Vaughan House, Shandon, Ohio, NRHP-listed Myrick–Yeates–Vaughan House, Murfreesboro, North Carolina, listed on the NRHP in North Carolina Rebecca Vaughan House, Courtland, Virginia, NRHP-listed Rev. Joshua Vaughan House, Coatesville, Pennsylvania, NRHP-listed Roberts-Vaughan House, Murfreesboro, North Carolina, listed on the NRHP in North Carolina Vaughan Homestead, Hallowell, Maine, listed on the NRHP in Maine William Hatchette Vaughan House, Molalla, Oregon, listed on the NRHP in Clackamas County, Oregon