Nikephoros I or Nicephorus I may refer to:

Nikephoros I Logothetes (ca. 760–811), Byzantine emperor in 802-811 Nikephoros I of Constantinople (ca. 750–828), Patriarch of Constantinople in 806–815 Nicephorus I of Kiev, Metropolitan bishop of Kiev, 1104–1121 Nikephoros I Komnenos Doukas (ca. 1240 – ca. 1296/8), Despot of Epirus in 1266/8–1296/8