The De Soto Open Invitational was a golf tournament on the PGA Tour that was held from March 24–27, 1960 at the De Soto Lakes Golf & Country Club in Sarasota, Florida. The club is now known as Palm-Aire Country Club and is located at Whitfield Avenue and Country Club Way. The event was won by then 47-year-old Sam Snead.

Winners YearWinnerScoreTo parMargin ofvictoryRunner-upWinner'sshare ($)Ref. 1960 Sam Snead 276 −8 1 stroke Jerry Barber 5,300

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