Waggener is a family name. Notable people with the name include:

John Waggener (1925–2017), U.S. Army officer Leslie Waggener (1841–1896), American professor and administrator Oliver G. Waggener, 13th Secretary of State of Kentucky Richard W. Waggener (1930–2018), member of the Wyoming House of Representatives

See also Waggoner (disambiguation) Wagener (surname)