Axapusco is a municipality in Mexico's State of Mexico. Its municipal seat is the town of Axapusco and largest town is . The municipality covers an area of 260.01 km2.

As of 2005, the municipality had a total population of 21,915

Politics MayorTime Florencio Amayo Pérez 2000–2003 Julián Cid González 2003–2006 Felipe Borja Texocotitla 2006–2009 Florencio Amayo Pérez 2009–2012 Gilberto Ramírez Ávila 2013–2015 Felipe Borja Texocotitla 2016–2018 Noé Martínez Juárez 2019–2021 Miriam Coronel Meneses 2022–2024 Melitón Cid Galicia 2025–2027

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