The Hospital of Santa Maria Nuova () remains the oldest and most influential hospital in Florence, Italy. Founded in 1288, this hospital was built from humble origins to a highly efficient, flourishing, and organized medical system through formalized laws and ordinances. This medical system included an intricate hierarchy of medical personnel, a wide breadth of medical services, and free services to all Florence citizens and visitors. Today, the hospital is still functioning and serves as the oldest running hospital in the world, currently serving the needs of the increased population and modern medical advances.
History
Origins The Hospital of Santa Maria Nuova was founded in 1288 by a wealthy Florentine merchant, Folco de Ricovero Portinari (d.1289). His family's servant, Monna Tessa (d. 1327), heavily convinced Portinari to found the hospital with an emphasis of charity and humility. Her dedication to service and healing is remembered at her tombstone alongside Folco, located in the Cloister of the Bones, and by her marble statue at the entrance of the hospital.Del Lungo, Isidoro. Women of Florence. LEGARE STREET PRESS, 2023. Folco's daughter, Beatrice (1265-1290), was the inspiration for Dante Alighieri's (1265-1321) Divine Comedy, though Beatrice and Dante were both married to other people and only met twice during their life.Zarevich, Emily. “Becoming Beatrice.” JSTOR Daily, 8 Nov. 2024, daily.jstor.org/becoming-beatrice/.
After the hospital's foundation on the former convent of a Catholic community, Sant’Egidio, the hospital rapidly transformed financially and physically from small beginnings to a large medical system with more than two hundred beds, multiple wards, ranks of medical professionals, and multidisciplinary care, all made possible by public subsidies and generous donations of wealthy Florence citizens.Lippi, Donatella Tombaccini, Donatella Lelli, Fiorella, and Rossi, Cristina. Florence and Its Hospitals. Firenze University Press Biblioteca Digital UCSH, pp. 92. The Hospital of Santa Maria Nuova was the first European medical institution to have a complex organization and still focus purely on healing the sick and the poor, regardless of financial status or place of origin.
Organization of the Hospital
Rules, orders, and layouts The Hospital of Santa Maria Nuova was particularly regarded for their progressive and modern rules, practices, and organizations. This hospital was an inspirational force throughout Europe; King Henry VII (1457-1509) of London requested two letters from Francesco Portinari, whose family founded the hospital, that described the ordinances and statues for the hospital that would help him later replicate their medical system in the Hospital of the Savoy. These ordinances included organization of staff, medical cures, and religious practices.Park, Katharine, and John Henderson. “‘The First Hospital among Christians’: The Ospedale di Santa Maria Nuova in Early Sixteenth-Century Florence.” Medical History, vol. 35, 1991, pp. 165.
Santa Maria Nuova had an intricately structured hierarchy of medical personnel, beginning with the rector as the administrative and medical oversight, who was supported by core medical staff including physicians, residents, and surgeons, as well as nurses, pharmacists, and a treasurer that allowed for the continuous and specialized care. First, the hospital's head figure, or rector, was a respectable, religious figure and voted in by two thirds of a majority. His life was set by strict guidelines, as he oversaw all medical practices and organizational tasks of daily schedules and professional ranks. The rector also held the responsibility of looking after the women's ward from a respectable distance, only visiting them once a month for reassurance. Administrative employees also include the treasurer and notary, who had the large responsibility of recording annual income and expenditures in extreme detail including charcoal, linens, wine, fruit, veggies, poultry, and materials for the pharmacy including herbs, leeches, and lancets. The notary dealt with legal matters, such as wills, leases, and contracts regarding property of the dead.Park, Katharine, and John Henderson. “‘The First Hospital among Christians’: The Ospedale di Santa Maria Nuova in Early Sixteenth-Century Florence.” Medical History, vol. 35, 1991, pp. 186.
The care of the sick in Santa Maria Nuova was also organized, with multiple layers of specialized care. The rector appointed the infirmarer, who was responsible for patient care and assisted by four deputies, each with seven nurses. Admission of the sick followed a strict procedure. If the ill couldn't arrive themselves, servants were sent to carry them to the hospital, an early version of medical transportation. When the patient was received, they were laid on a covered bed in the middle of the infirmary, where the infirmarer determined the nature of illness and the nurse washed the feet, emphasizing their focus on cleanliness. The patient was then assigned an admission number and a number to a bed, which was lined with linens, pillows, and additional covers depending on the season: wool for winter, linen for summer.Henderson, John Henderson. “The Renaissance Hospital: Healing the Body and Healing the Soul.” Yale University Press, 2006, pp. 164.
Next, the sub-informer oversaw the organization of the linens, and took in the patient by noting the patient's name, father's name, location of origin, family name, and amount of money. They also stripped the patient of their clothes and stored them in the Pergola, where the bags were organized alphabetically. Once assigned to a ward, patients were visited daily by three resident physicians, who report to six senior physicians. These senior doctors met each morning with the pharmacist, infirmarer, and one resident doctor to review each patient's illness and past treatments, where they were further prescribed more medication that was recorded by the pharmacist to prepare.Park, Katharine, and John Henderson. “‘The First Hospital among Christians’: The Ospedale di Santa Maria Nuova in Early Sixteenth-Century Florence.” Medical History, vol. 35, 1991, pp. 173-174.
Diet was considered one of the best treatments and was specialized to each patient and illness. While chicken broth was the staple meal, different foods and wines were prescribed based on the humoral balance of the patient. The organization of food distribution ensured that food was delivered efficiently and cleaned afterward. During meal times, nurses went through each room to ensure the patient was eating, and noted if they needed assistance or failed to eat. Also, servants circulated the hospital three times per day and asked patients which sweet they would like.Park, Katharine, and John Henderson. “‘The First Hospital among Christians’: The Ospedale di Santa Maria Nuova in Early Sixteenth-Century Florence.” Medical History, vol. 35, 1991, pp. 173.
Despite the emphasis of physical care, Santa Maria Nuova still emphasized religion into hospital life. All medical staff living in the hospital were required to take sacraments, attend confession, and take communion. A sacristan oversaw religious activities of the staff and patients. The patients received sacraments depending on their condition, and were organized on a public board into stages of confession, Eucharist, commendation of the soul to God, and extreme function for those near death. When patients were close to death, they were brought an image of Christ on the cross, with the nurses staying by the bedside reading holy texts. After death, the nurse prepared the body and clothed them to be placed near the middle of the hospital by the church. Once prepared, lay brothers would transport the body to a funeral service to be buried.Park, Katharine, and John Henderson. “‘The First Hospital among Christians’: The Ospedale di Santa Maria Nuova in Early Sixteenth-Century Florence.” Medical History, vol. 35, 1991, pp. 183.
Physical organization of the hospital
The hospital has a clear physical organization that was conducive to the flow of medical personnel and extensive practices. The hospital was organized into multiple wards, including separate men and women's wards, the church of Sant’Egidio at the center, and supporting rooms surrounding the hospital such as the kitchen, pharmacy, and administrative rooms. The men's ward was the most developed department since it was founded first, growing to one hundred beds by the 1500s.Park, Katharine, and John Henderson. “‘The First Hospital among Christians’: The Ospedale di Santa Maria Nuova in Early Sixteenth-Century Florence.” Medical History, vol. 35, 1991, pp. 171. The women's ward was separate from the men's, with an emphasis on having its own female nurses and medical staff. The hospital's church of Sant’Egidio served as the center for patient healing, symbolizing healing as a physical and spiritual process. The medicinarium was a separate clinical space that was not only used for surgery, but also outpatient care and minor treatments for those who could not afford in-home care.Park, Katharine, and John Henderson. “‘The First Hospital among Christians’: The Ospedale di Santa Maria Nuova in Early Sixteenth-Century Florence.” Medical History, vol. 35, 1991, pp. 172. Additionally, the pharmacy was a separate room with twenty two vessels for distilling and an intricate system for preparing medications and storing ingredients. The pharmacy was dependent on the garden founded in the 15th century, since it provided all of the plants used in medicines and distillery.Gozzoli, Antonella. “Ospedale Di Santa Maria Nuova.” Scientific Itineraries, brunelleschi.imss.fi.it/itineraries/place/OspedaleSantaMariaNuova.html. Accessed Apr. 2026. The kitchen was also a key aspect of the hospital, as they were known for using specialized diets as a part of treatment, especially chicken soup. The hospital also included living quarters for lay brothers and medical staff that had strict guidelines for who can enter and visit. Courtyards and open spaces served as treatment since “bad air” was believed to be unhealthy and associated with illness.Henderson, John Henderson. “The Renaissance Hospital: Healing the Body and Healing the Soul.” Yale University Press, 2006, pp. 161.
Presently, the Hospital of Santa Maria Nuova is still functioning, making it the oldest continuously operating hospital in the world. While the structure and physical architecture is preserved, the facility has changed to meet modern medical standards. Some department and hospital services offered today include emergency medicine, general surgery, dermatology, psychiatry, radiology, and neurology.“Santa Maria Nuova Hospital.” Reggio Emilia, www.reggioemiliawelcome.it/en/reggio-emilia/trade-fairs-and-convention-services/useful-services/health/santa-maria-nuova-hospital. Accessed 15 Apr. 2026.
Medical practice