PRK can refer to:
North Korea, ISO 3166-1 alpha-3 code Photorefractive keratectomy, laser eye surgery Phase reversal keying, a form of phase-shift keying People's Republic of Korea, short-lived 1945 government People's Republic of Kampuchea, 1979-1989 Port Kent (Amtrak station), New York, US station code Phosphoribulokinase, an enzyme Puneeth Rajkumar, an Indian Kannada-language film actor