1,3-Diaminopropane, also known as , is a simple diamine with the formula H2N(CH2)3NH2. A colourless liquid with a fishy odor, it is soluble in water and many polar organic solvents. It is isomeric with 1,2-diaminopropane. Both are building blocks in the synthesis of heterocycles, such as those used in textile finishing, and coordination complexes. It is prepared by the amination of acrylonitrile followed by hydrogenation of the resulting aminopropionitrile.Karsten Eller, Erhard Henkes, Roland Rossbacher, Hartmut Höke "Amines, Aliphatic" in Ullmann's Encyclopedia of Industrial Chemistry, Wiley-VCH, Weinheim, 2005.
The potassium salt was used in the alkyne zipper reaction. Applications
Spermidines, imipramine, and phenothiazine-type structures, eprobemide, cannabisativine, codonocarpine, palustridine, palustrine, oncinotine & pithecolobine have 1,3-diaminopropane in their structures.
Safety 1,3-Diaminopropane is toxic on skin exposure with an of 177 mg kg−1 (dermal, rabbit)
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