Griffith House or Griffiths House may refer to:
Robert G. Griffith Sr. House, Summit, Alabama, listed on the NRHP in Alabama Bateman-Griffith House, Clarendon, Arkansas, listed on the NRHP in Arkansas Griffith House (Penryn, California), listed on the NRHP in California Griffiths House (Opa-Locka, Florida), listed on the NRHP in Florida John W. Griffiths Mansion, Chicago, Illinois, listed on the NRHP in Illinois Pierson-Griffiths House, Indianapolis, Indiana, listed on the NRHP in Indiana E. H. Gibbs House, in Oskaloosa, Iowa, also known as Griffith Hall Griffith-Franklin House, Calhoun, Kentucky, listed on the NRHP in Kentucky D. W. Griffith House, La Grange, Kentucky, listed on the NRHP in Kentucky Griffith House (Midway, Kentucky), listed on the NRHP in Kentucky Griffith House (Aberdeen, Maryland), listed on the NRHP in Maryland Griffith-McCune Farmstead Historic District, Eolia, Missouri, listed on the NRHP in Missouri James Griffith House, Canal Winchester, Ohio, listed on the NRHP in Ohio William R. Griffith House, Harrisburg, Pennsylvania, listed on the NRHP in Pennsylvania David Jefferson Griffith House, Gilbert, South Carolina, listed on the NRHP in South Carolina James Turk Griffith House, Ten Mile, Tennessee, listed on the NRHP in Tennessee Jenner-Griffiths House, Minersville, Utah, listed on the NRHP in Utah J. W. Griffiths House, Port Townsend, Washington, listed on the NRHP in Washington Griffiths House (Alice Springs), a Methodist children's home and hostel in Australia