Distemper may refer to:
Illness A viral infection Canine distemper, a disease of dogs Feline distemper, a disease of cats Phocine distemper, a disease of seals A bacterial infection Equine distemper, or strangles, a bacterial infection of the horse Derangement or disturbance of the four humours or "temper", in pre-modern medicine
Other uses Distemper (paint), a decorative paint and a historical medium for painting pictures Distemper (band), a Russian ska punk band Distemper (album), by The New Christs Remix dystemper, a remix album by Skinny Puppy
See also Murrain, a name of any of a number of serious illnesses among cattle and sheep, for which the name 'Distemper' was used in mid 18th century England.