Farghānī (, meaning from Farghāna), or Al-Farghani is a common surname in Central and Western Asia and was a common nisbat in the medieval Islamic world. It may refer to the following: Ahmad ibn Muhammad ibn Kathīr al-Farghānī, also known as Alfraganus, a 9th-century astronomer Rustum ibn Bardu al-Farghani, 10th-century Abbasid commander and governor of Tarsus Siraj al-Din al-Ushi al-Farghani, 12th century Hanafi-Maturidi scholar Sayf-i Farghānī, a 13th-century Persian poet Sa'id al-Din Farghani, a 13th-century Sufi author Abu Abdullah b. Ahmad b. Ja'far al-Farghani, the student of al-Tabari who wrote the appendix, al-Sila, to History of the Prophets and Kings.
See also Fergani (disambiguation), a surname of North African origin