COI, CoI or Coi may refer to:

Organizations Center on Organizational Innovation, a research center at Columbia University Central Office of Information, a former UK Government department Church of Ireland, an autonomous province of the Anglican Communion College of Idaho, a university Commission de l'Océan Indien, or Indian Ocean Commission

Science and technology California Oregon Intertie or Path 66, an electrical power transmission system Centre of inertia Coefficient of Inbreeding, the probability that two alleles at a given locus are identical by descent Community of inquiry, a concept describing the social quality of scientific inquiry Community of interest (computer security), a computer networking technique of segregation of resources Confirmed opt-in, a policy for obtaining mailing list recipients Contingency Orbit Insertion, an abort mode of the Apollo spacecraft Cost of illness, see Disease burden Cytochrome Oxidase Subunit 1, a gene Coprocessor Offload Infrastructure, a high-level software library for code and data offloading to a Xeon Phi Coprocessor

Other uses Comoros, UNDP country code Commission of inquiry (disambiguation) Constitution of India Conflict of interest Certificate of insurance Certificate of incorporation Coi (restaurant), restaurant in San Francisco, California Dennis Coi (died 1987), Canadian figure skater Trịnh Cối (died 1584), Vietnamese de facto ruler of Southern dynasty Coi (album), a 2023 album by Coi Leray

See also Coy (disambiguation) Koi (disambiguation)