Pontypool is a town in Wales, United Kingdom.

Pontypool may also refer to:

Pontypool (UK Parliament constituency) which had included the Welsh town. Pontypool RFC, Welsh rugby union team from Pontypool. Pontypool, Ontario, Canada - named for the Welsh town and birthplace of their first settlers. Pontypool (film), 2008 Canadian horror film set in the Canadian village of Pontypool.

See also Pontypool Changes Everything, 1995 fiction novel