Empress Guo may refer to:
Guo Shengtong (6–52), wife of Emperor Guangwu of Han Guo Nüwang (184–235), wife of Emperor Wen of Cao Wei Empress Guo (Cao Rui's wife) (died 264), wife of Emperor Ming of Cao Wei Empress Dowager Guo (Tang dynasty) (died 848), wife of Emperor Xianzong of Tang Empress Guo (Zhenzong) (975–1007), wife of Emperor Zhenzong of Song Empress Guo (Renzong) (1012–1035), wife of Emperor Renzong of Song Empress Xiaoyuanzhen (1580–1613), wife of the Taichang Emperor