Alkali Lake may refer to:
A soda lake or "alkaline lake" (a lake with high alkalinity)
In Canada Alkali Lake, British Columbia Alkali Lake Indian Band, First Nations government of the Secwepemc (Shuswap) people in British Columbia
In the United States Alkali Lakes, playas in northeastern California Alkali Lake Chemical Waste Dump, hazardous waste disposal site in Oregon Alkali Lake, a playa in Oregon Alkali Lake State Airport, airport in Oregon Alkali Lake in Blaine County, Montana Alkali Lake in Lincoln County, Montana Alkali Lake in Glacier County, Montana Alkali Lake in Meagher County, Montana Alkali Lake in Pondera County, Montana Alkali Lake in Toole County, Montana Alkali Lake (Lander and Pershing counties, Nevada), a lake in Nevada
In fiction Alkali Lake, a fictional location in the X-Men universe, portrayed in films using the real-life Barrier Lake