Holtzmann is a surname. Notable people with the surname include:
Adelheid Holtzmann (1866–1925), German politician and women's rights activist Adolf Holtzmann (1810–1870), German philologist Fanny E. Holtzmann (1902–1980), pioneering female lawyer Heinrich Julius Holtzmann (1832–1910), German theologian Oskar Holtzmann (1859–1934), German theologian Robert Holtzmann (1873–1946), German Medievalist historian
See also Holtzmann's law