Palen or Palén is a surname. Notable people with the surname include:

Anna von Palen (1875–1939), German actress Cole Palen (1925–1993), American flier & collector Fyodor Palen (1780–1863), Russian diplomat and administrator Paul Palén (1881–1944), Swedish shooter Rufus Palen (1807–1844), American politician Tim Palen, American motion picture marketing executive and photographer

See also Palen Mountains, northern Colorado Desert, California, USA Palen Creek Correctional Centre, about 100 km south west of Brisbane Frank A. Palen House, historic home located at Kingston in Ulster County, New York Frederic Palen Schoonmaker (1870–1945), United States federal judge Palin Pahlen