Paykull, also spelled Paydkull, Paytkull, Paiküll, Paijkull, Pajkul or Paykel is a Swedish-Livonian/Estonian/Baltic German family name. It may refer to:

Göran Paijkull (1605–1657), Swedish soldier and riksråd Otto Arnold von Paykull (1662–1707), Livonian general and alchemist Gustaf von Paykull (1757–1826), Swedish Marshal of the Court, ornithologist and entomologist Wilhelm Paijkull (1836–1869), geologist, chemist Carl Wilhelm Paijkull Gunilla Paijkull

sv:Paykull