Accomac may refer to:

Geography Accomac, Virginia, a town in Virginia Accomac Shire, a former county in Virginia of which the town was the county seat Accomac, Pennsylvania

Peoples Accomac people, a historic Native American tribe from the Eastern Shore of Virginia

Ships , three ships of the US Navy

See also Accomack County, Virginia, the current incarnation of Accomac Shire Plymouth, Massachusetts was built on a site identified on early maps as Accomack