The Last of Mrs. Cheyney may refer to:

The Last of Mrs. Cheyney (play), a 1925 play by Frederick Lonsdale The Last of Mrs. Cheyney (1929 film), a 1929 adaptation starring Norma Shearer and Basil Rathbone The Last of Mrs. Cheyney (1937 film), a 1937 adaptation starring Joan Crawford and William Powell The Last of Mrs. Cheyney (1961 film), a 1961 adaptation starring Lilli Palmer

See also The Law and the Lady (1951 film), an adaptation starring Greer Garson