Mifsud is a surname of Maltese origin. Notable people with the surname include:
Adrian Mifsud (born 1974), Maltese footballer Anthony J. Mifsud, Maltese-Canadian actor, singer and songwriter who performs as Mif Carmelo Mifsud Bonnici (born 1960), Maltese politician, son of Ugo Mifsud Bonnici Daniel Mifsud (born 1983), Australian Idol contestant George Mifsud Chircop (1951–2007), Maltese linguist Giuseppe Mifsud Bonnici (1930–2019), Maltese Chief Justice and philosopher Immanuel Mifsud (born 1967), Maltese writer Jean Pierre Mifsud Triganza (born 1981), Maltese footballer Josef Mifsud (born 1984), Maltese footballer Joseph Mifsud (born 1960), Maltese academic Karmenu Mifsud Bonnici (1933–2022), former Prime Minister of Malta Ludovik Mifsud Tommasi (1796–1879), Maltese priest, educator and poet Michael Mifsud (born 1981), Maltese footballer Paul Mifsud, Maltese snooker player Paula Mifsud Bonnici, member of Parliament of Malta (2013–2017) Philip Mifsud (born 1971), Maltese architect and politician Sigmund Mifsud, Maltese musician and conductor Stéphane Mifsud (born 1971), French free-diver Steve Mifsud (born 1972), Australian snooker player Ugo Mifsud Bonnici (born 1932), former President of Malta Ugo Pasquale Mifsud (1889–1932), former Prime Minister of Malta