Leininger is a surname. Notable people with the surname include:
Claus Leininger (1931–2005), German theatre director and manager Dannette Leininger (born 1963), American handball player James Leininger (born 1998), American child reincarnation case James R. Leininger, American businessman Madeleine Leininger (1925–2012), American nurse
See also Leininger Peak, mountain of Antarctica