Gastón Gaudio was the defending champion, but lost to Rubén Ramírez Hidalgo in the second round this year.
José Acasuso won the title, defeating Nicolás Massú 6–4, 6–3 in the final.
This was the first ATP tournament in which future Grand Slam champion Juan Martín del Potro entered.
Seeds
Gastón Gaudio (second round) Fernando González (semifinals) José Acasuso (champion) Agustín Calleri (first round) Nicolás Massú (final) Albert Montañés (quarterfinals) Carlos Berlocq (first round) Boris Pašanski (quarterfinals)
Draw
Finals
Top half
Bottom half
References
External links 2006 Movistar Open draw 2006 Movistar Open qualifying draw