Manlius may refer to:
Places in the United States Manlius, Illinois Manlius (town), New York Manlius (village), New York Manlius Township (disambiguation) Manlius Township, Bureau County, Illinois Manlius Township, LaSalle County, Illinois Manlius Township, Michigan
Other uses Manlius (1826 ship) Manlius Pebble Hill, a school in DeWitt, New York any of various Romans belonging to the gens Manlia