William Kane may refer to:
William Francis de Vismes Kane (1840–1918), English entomologist William R. Kane (1911–1957), United States Navy captain and World War II flying ace. Will Kane, a fictional character Billy Kane, a video game character
See also William Kane Reilly, administrator of the Environmental Protection Agency William Cane (disambiguation) William Cain (disambiguation) William Caine (disambiguation) Kane (surname)