A disease is an abnormal condition that affects the body of an organism.

Disease or The Disease may also refer to:

Disease (Beartooth album) or the title song, 2018 Disease (G.G.F.H. album) or the title song, 1993 The Disease EP or the title song, by the Eyes of a Traitor, 2011 "Disease" (Matchbox Twenty song), 2002 "Disease" (Lady Gaga song), 2024 "Disease", a song by Hollywood Undead from Day of the Dead, 2015 "Disease", a song by Insight 23 from Obsess, 1995 "Dis-ease", a song by BTS from Be, 2020 "The Disease", a song by Heaven Shall Burn from Iconoclast (Part 1: The Final Resistance), 2008 "The Disease", an episode of Star Trek: Voyager

See also List of diseases