HCU may refer to:
Universities Heritage Christian University, in Florence, Alabama, United States Hiroshima City University, in Japan Houston Christian University, in Texas, United States Hsuan Chuang University, in Hsinchu City, Taiwan Huachiew Chalermprakiet University, in Samut Prakan, Thailand Hyderabad Central University, in India
Other uses Heavy Conversion Unit, of the Royal Air Force Homocystinuria Hyundai Chungun High School, in Dong-gu, Ulsan, South Korea High Care Unit Hydraulic Control Unit