Giacomelli () is an Italian surname derived from the given name Giacomo (James). Notable people with the surname include:
Bruno Giacomelli (born 1952), Italian race car driver Cesare de' Giacomelli (died 1577), Italian Catholic prelate Francesco Giacomelli (born 1957), Italian ski jumper Geminiano Giacomelli (1692–1740), Italian composer Giacomo de' Giacomelli (), Italian Catholic prelate Giorgio Giacomelli (1930–2017), Italian diplomat Guido Giacomelli (born 1980), Italian ski mountaineer Hector Giacomelli (1822–1904), French watercolorist, engraver and illustrator Mario Giacomelli (1925–2000), Italian photographer Nella Giacomelli (1873–1949), Italian anarchist, teacher and journalist Raffaele Giacomelli (1878–1956), Italian aeronautical engineer Sophie Giacomelli (1779–1819), French painter and engraver Stefano Giacomelli (born 1990), Italian footballer Tommy Giacomelli (born 1974), Brazilian footballer
See also 15567 Giacomelli (2000 GF53), a main-belt asteroid Giacomel Giacometti (surname) Giacomini (surname) Giacomellia, a genus of moths Archytas giacomellii, a species of fly Argyrargenta giacomellii, a species of moth Hypopta giacomelli, a species of moth Trichopodopsis giacomellii, a species of fly