Margaret Howe may refer to:
Margaret Howe (squash player) (1897–1989), American squash player Margaret Howe (athlete) (born 1958), Canadian sprinter Margaret Howe Lovatt (born 1942), American naturalist Margaret Ascham (c. 1528 – c. 1592), English writer Margaretta Brucker (pseudonym Margaret Howe), American fiction author Margaret Vale (married name Howe; 1878–?), American actress and feminist