William Hume may refer to: Bill Hume (footballer) (1937–2005), English-born soccer player who played for New Zealand and Australia Bill Hume (cartoonist) (1916–2009), American artist, art director, and newspaper man Billy Hume (1935–1990), Scottish footballer Willie Hume (1862–1941), cyclist, first ever winner on Dunlop pneumatic tyres William Hume (Cape politician) (1837–1916), politician of the Cape Colony William Errington Hume (1879–1960), English physician (knighted in 1952) William H. Hume, American architect in New York City William J. Hume, American heir, businessman and conservative philanthropist William Fraser Hume (1867–1949), British geologist
See also William Hume-Williams (1863–1947), British politician William Hume Blake (1809–1870), Canadian jurist and politician William Hume-Rothery (1899–1968), British metallurgist William Hulme (disambiguation)