U-106 may refer to one of the following German submarines:
, a Type U 93 submarine launched in 1917 and that served in the First World War until sunk on 7 October 1917 north of Terschelling in Netherlands. During the First World War, Germany also had this submarine with a similar name: , a Type UB III submarine launched in 1917 and surrendered on 26 November 1918; dumped on beach at Falmouth after explosive trials 1921 and broken up in situ , a Type IXB submarine that served in the Second World War until sunk on 2 August 1943