Tweak or Tweaker may refer to:
Computing Tweaking, the act of making small mechanical or electronic improvements Tweak programming environment, a graphical user interface layer for the Squeak development environment Tweak UI, a utility program for Microsoft Windows Tweakers, a Dutch technology website Tweak7, a Windows software tool
Other Tweak (company), an Irish graphic design company Tweak (band), a South African musical group Tweaker (band), an American musical group "Tweaker" (song), by LiAngelo Ball Stereotypy, or tweaking, exhibiting compulsive or repetitive behaviour TWEAK, a cytokine encoded by the gene TNFSF12 Tweak, a character filmed in Octonauts
See also Tweek (disambiguation)