Humphrys is a surname. Notable people with the surname include:
Bob Humphrys (1952–2008), BBC Wales sports broadcaster Fletcher Humphrys (born 1976), Australian actor Sir Francis Humphrys (1879–1971), British colonial administrator and diplomat John Humphrys (born 1943), BBC broadcaster Stephen Humphrys, English footballer William Humphrys (1794–1865), Irish engraver
See also Humfrey, given name and surname Humphery, surname Humphrey, given name and surname Humphreys (surname) Humphry, surname Humphries, surname