Thomas Burke or Tom Burke may refer to:

Artists and entertainers Thomas Burke (artist) (1749–1815), Irish engraver and painter known for mezzotint Thomas Burke (author) (1886–1945), English poet and author Thomas Burke (tenor) (1890–1969), British operatic tenor Tom Burke (actor) (born 1981), English actor

Clergymen Thomas Burke (bishop) (circa 1709–1776), Irish Roman Catholic clergyman Thomas Nicholas Burke (1830–1882), Irish Roman Catholic theologian and preacher Thomas Martin Aloysius Burke (1840–1915), Irish-born Roman Catholic clergyman Tom Burke (priest) (1923–2008), Irish Carmelite priest, physicist and schoolteacher

Politicians and government officials Thomas Burke (Clare politician) (1876–1951), Irish legislator Thomas Burke (North Carolina politician) (c. 1747–1783), Irish-born physician, lawyer and politician Sir Thomas Burke, 3rd Baronet (1813–1875), Irish legislator Thomas A. Burke (1898–1971), American Democratic city executive and legislator Thomas Henry Burke (civil servant) (1829–1882), Irish Catholic Permanent Under Secretary in Britain's Irish Office Thomas Henry Burke (politician) (1904–1959), American politician Tom Burke (Australian politician) (1910–1973), Labor Party legislator for the Division of Perth Sir Thomas Kerry Burke (born 1942), New Zealand Labour Party Member of Parliament T. J. Burke (Thomas James Burke, born 1972), American-born Canadian legislator

Sportsmen Tom Burke (footballer, born 1862) (1862–1914), Welsh footballer Tom Burke (hurler) (fl. 1865–1887), Irish hurler Thomas Burke (sprinter) (1875–1929), American sprinter, first Olympic champion in the 100 m and 400 m races Tom Burke (American football) (born 1976), American National Football League player Tom Burke (Irish footballer), Ireland footballer

Soldiers Thomas Burke (Medal of Honor sailor) (1833–1883), U.S. Navy sailor and peacetime Medal of Honor recipient Thomas Burke (Medal of Honor soldier) (1842–1902), Medal of Honor recipient Tom Burke (RAF officer), British senior Royal Air Force air vice-marshal

Others Thomas Burke (businessman) (1870–1949), Australian businessman and philanthropist Thomas Burke (railroad builder) (1849–1925), American jurist and railroad builder Thomas E. Burke (1864–1941), Irish-born American labor union leader Thomas J. Burke (North Dakota judge) (1896–1966), American jurist; justice of North Dakota Supreme Court Thomas Ulick Burke (1826–1867), bank manager and victim of the Break-o-Day murder in gold-rush Victoria Tom Burke (environmentalist) (born 1938), British academic and writer on environmental policy issues Tom Burke (Irish revolutionary and sportsman) (1894–1967), Irish revolutionary, sportsman and referee William Burke (pirate) (died 1699), sometimes known as Thomas Burke, Irish pirate active in the Caribbean, associate of William Kidd

Fictional characters Thomas Burke, in the video game Mafia III Officer Thomas Burke, in the movie Final Destination 2.

See also Tomás Burke (fl. 1600–02), Irish gentleman and soldier Burke (surname) Tommy Burks (1940–1998), American Democratic legislator in Tennessee