S43 may refer to:
Submarines , of the Royal Navy , of the Indian Navy , of the United States Navy
Other uses County Route 563 (New Jersey), designated New Jersey Route S43 until 1953 County Route S43 (Bergen County, New Jersey) Harvey Airfield, in Snohomish, Washington, United States Sikorsky S-43, an American flying boat Sulfur-43, an isotope of sulfur S43, a postcode district in Chesterfield, England