Charles Byrne may refer to:
Charles Byrne (giant) (1761–1783), also known as "The Irish Giant" Charles Alfred Byrne (1848–1909), American journalist and playwright Charles C. Byrne (1837–1921), brigadier general in the United States Army Charles Byrne (artist) (1757–1810?) , Irish painter of miniatures Charlie Byrne (footballer) (1895–1924), Australian rules footballer Charlie Byrne (baseball) (1843–1898), original owner of the Brooklyn Dodgers baseball team
See also Charles Burns (disambiguation)