R50 or R-50 may refer to:
Automobiles BMW R50, a motorcycle Mini Hatch (R50), a hatchback Nissan Pathfinder (R50), a sport utility vehicle Toyota LiteAce (R50), a van Venucia R50, a hatchback Volkswagen Touareg R50, a sport utility vehicle
Other uses R50 (South Africa), a road , a destroyer of the Royal Navy R-50, the ASHRAE designation for methane as a refrigerant R50: Very toxic to aquatic organisms, a risk phrase R50, a commuter rail service on the Llobregat–Anoia Line, in Barcelona, Catalonia, Spain R50, a Ferris wheel designed by Ronald Bussink Canon EOS R50, crop-frame mirrorless camera