Wakeham is an English surname. Notable people with the surname include:
Bill Wakeham (born 1944), British chemical engineer Brandon Wakeham (born 1999), Fijian international rugby league footballer Janeiro Wakeham (born 2003), Fijian professional rugby union footballer John Wakeham (born 1932), British businessman and politician Peter Wakeham (1936–2013), English footballer Tony Wakeham (born 1956), Canadian politician from Newfoundland and Labrador