N22 may refer to:

Roads N22 road (Belgium) Route nationale 22, France N22 road (Ireland) Nebraska Highway 22, United States

Bus routes London Buses route N22 N22 (Long Island bus), New York

Other uses Atlas V N22, an American expendable launch system GAF N22 Nomad, an Australian utility aircraft Nitrogen-22 an isotope of nitrogen Sky Manor Airport (North Carolina), United States, serving Jacksonville N22, a postcode district in the N postcode area of London