Genome (, Genom) is a science fiction/detective novel by the popular Russian sci-fi writer Sergei Lukyanenko. The novel began a series also called Genome, consisting of Dances on the Snow (a prequel, although written later) and Cripples (a sequel). The novel explores the problems of the widespread use of human genetic engineering, which alters not only human physiology but also psychology.

The Universe The novel takes place in the latter half of the 22nd century. Humans have left their cradle, colonized numerous extrasolar planets, and made contact with extraterrestrials, or "aliens", as most humans call them, even though such term is not considered to be politically correct. All humans are subjects of the Empire, ruled by a small child, although all decisions are made by the Imperial Council in his name. After the end of the conflicts between the Empire and the aliens several decades prior, the galaxy is, mostly, at peace, although relations are still tense between many of the species. To maintain the peace, the Empire was forced to quarantine its own colony of Ebon, which contained a large part of the Imperial military industry and provided a sizable percentage of soldiers. The ideology of the people of Ebon, formed by the ruling Church of the Angered Christ, demands the complete extermination of all alien life in the Universe to make way for the true children of God — humans. The fleet of Ebon was annihilated, and the planet itself was placed under a quarantine shield. Any Ebonite found outside the shield was forced to undergo deep psychotherapy.

Alien Races Czygu: while on the outside they are similar to Earth insects, their biological makeup is radically different. They are roughly human-sized and can even be mistaken for a human in appropriate attire. Their bodies naturally produce mercaptan (which caused humans to call them "stinkies" on occasion), which forces them to wear full body suits or ingest special medicine to suppress the emission of odorous substances when visiting human worlds. They possess technology allowing them to biologically transform their exterior appearance to match that of the humans. In this form, a Czygu female is nearly indistinguishable from a young human female. Czygu live in close communities, similar to Earth beehives or anthills, with strict hierarchy and rules of behavior. The Czygu are ruled by the privileged females, while most of the jobs are performed by male drones, who have only recently attained self-awareness (a mindless drone would be unable to operate complex equipment). Drones have absolute loyalty to their rulers built into their genes. The Czygu are in a state of conflict with the Brauni. Brauni: very little is mentioned in the novel about them. Apparently, they are extremely warlike. Civilian ships are advised to stay away from special zones which are sites for Brauni ritual battles. They periodically enter into a state of battle madness, become extremely aggressive and completely out-of-control — a threat to anyone around them. The Brauni are in a state of conflict with the Czygu. Fanhuan: almost nothing is known about this race. They are described as slow creatures with pseudo-wings. Taii: an ancient sentient race, a former galactic superpower. After a devastating interstellar war with an unknown foe, the Taii were victorious, but it was a Pyrrhic victory, as the damage they sustained turned out to be unrepairable. They inhabit a mere several dozen worlds, have long ago stopped expanding, and are slowly dying out. While gigantic Taii starships still patrol space, which used to be theirs, they present little threat to modern warships (it has been stated that a small human destroyer is capable of completely incinerating a colossal Taii ship with a single barrage). Halflings: short, stout humanoids, covered with profuse body hair. Very little else is mentioned in the novel.

Speshes and clones Humanity continues the eugenic practice started long ago (in this regard, the novel is reminiscent of Lukyanenko's short story The Road to Wellesberg). Even as far back as the 21st century, methods were developed allowing the alteration of a human's genotype to adapt him or her to a particular position. Such operation (or "specification") is performed on a just-conceived fetus at the request of the parents, who, by doing this, forever decide the future of their child. Specified humans are called "specs", while non-modified humans are labeled "naturals". The cost of specification, the possibility of getting a credit for the procedure, and other conditions depend on the planet's demand in the requested profession. Specs are genetically compatible with naturals, as the former retain their non-modified genotype, and specified genes are only passed on if both parents possess them; however, the latter case still remains a choice on the parents' part. This allows the retention of specification without the help of geneticists (but only if the speshes wish for their children to have the same specification) but also allows the return to the original genotype in just one generation.

Even during early childhood, a future spesh develops brilliant abilities and a great interest in his or her future profession. The metamorphosis occurs around puberty, which involves the restructuring of the body and mind to match the specification. This takes place within several hours, usually under the watchful eye of a doctor. During this time, the person is completely helpless and does not perceive his or her surroundings. First, the body restructures itself, then the same thing happens to the psyche and the intellect, the latter being the most difficult and dangerous part of the metamorphosis. The spec's genetically-imprinted knowledge is activated; the visions experienced differ depending on the particular specification. For example, a master-pilot sees him- or herself flying through space, feeling completely happy. The undesirable abilities are suppressed. For example, pilots, detectives, and tax inspectors lose their ability to love, so that extraneous emotions do not interfere with their duties.

After the metamorphosis, no matter the actual age, the spec attains the full legal status of an adult and a rightful citizen of the Empire. However, not all knowledge is preprogrammed into the specs, and they are still required to attend schools and academies. Legally, a spec has a right to remove any genetic alteration, if he or she is unhappy with his or her current position. However, practically, this is unrealistic — first of all, not all changes are reversible, and second, as part of the metamorphosis, the spec is conditioned to completely love his or her job.

After completing training, a spec spends the rest of his or her life doing his or her favorite job, loving it and understanding that the job is done well. Every spec possesses immunity from most known diseases. They are highly paid and possess a higher social status than naturals, as well as higher respect among the fellow specs. It is said that "specs are happy from the cradle to the grave". A spec can only become unhappy if he or she is not allowed to perform his or her job or is incapable of performing it, although the latter is usually due to external reasons.

Most naturals do not have as high a salary as the specs and are usually forced to take on jobs that do not require special skills (valets, waiters, etc.). On the other hand, true creative jobs cannot be specified. There are no writers-spec or scientists-spec. Attempts at creating businessmen-spec and politicians-spec have also been largely unsuccessful. All of these professions belong to the naturals. Extraordinary naturals have been known to perform certain jobs on par with specs, although these cases are rare. The exceptions include jobs which a natural is physiologically unable to perform, such as an energetic-spec, who works directly with reactors and must be able to handle lethal doses of radiation. Also, almost no natural is completely unmodified, as several more general modifications are used by virtually everyone, including visual correction to fix bad eyesight and neural shunts allowing direct brain-to-computer interface.

Besides specs and naturals, there is also a third group of people: they are genetically modified but lack any moral restrictions programmed into speshes.

The need for colonization of new worlds led to underpopulation, which was partially compensated by mass cloning. Many clones currently live in the Empire, having the same legal rights as normal humans but are traditionally named after their prototype with "C-number" as a middle name (e.g. Andrey C-third Sidorov is the third clone of a man named Andrey Sidorov). All attempts to clone geniuses failed, as their clones have been unable to do any of the things their prototypes did. However, best specs are actively cloned.

Xenophobia is still present in human society: most specs see themselves as the naturals' betters, while the naturals tend not to like specs; also, many normal humans have misgivings about clones; and, of course, there is the distrust and dislike most humans feel for aliens.

Several specifications Master-pilotSpecification: piloting of a spaceship. Captains are usually selected from pilots.Enhanced vision. Precisely determines distance (to the nearest centimeter, if the distance is less than 10 meters) and speed of any visible object. Increased tolerance to acceleration. Retains mobility up to 6 g and manual dexterity up to 12 g. Can jump from a height of 10 meters without any ill effects. After a dangerous car accident, can get up and walk away without so much as a broken bone. Enhanced hand-eye coordination. Instinctively attempts to maintain maximally stable position in any location (even planetside). Feels discomfort if the body position is potentially dangerous. Enhanced memory and logical reasoning. Possesses built-in psychological knowledge.Personality characteristics: honesty, goodness, loyalty, sense of duty, courage. A pilot must, if necessary, give his or her life to save the lives of the passengers. Incapable of denying aid to anyone he or she perceives as entrusted to him or her (could be a crew member, a passenger, any other human who happens to be under the pilot's wing).Pilots' ability to love is artificially suppressed. Instead, they have the ability to love their ship.Enhanced moral qualities forbid the pilot from engaging in immoral actions; however, law-abiding qualities in of themselves have not been enhanced. Personal moral code is more important for a pilot than the law. This is due to the fact that pilots visit numerous worlds, each of which has different laws. As such, it would be dangerous to stick to one particular set of rules. EnergeticSpecification: operation of power plants. This profession is spec-only.Physical abilities: able to determine temperature of a flame to a thousandth of a degree at a glance, eyes modified to perceive a wider spectrum of radiation and energy. The energetic's organism is specially-conditioned to resist radiation lethal to others, which requires the alteration in the makeup of the skin. Long hair acts as an anti-radiation screen, protecting the head. Male energetics are capable of pulling testicles into their bodies while working.