Rupe may refer to:
Places: Rupe, Mozambique, a settlement in Mozambique Rupe, Celje, a village in the City Municipality of Celje, eastern Slovenia Rupe, Velike Lašče, a village in the Municipality of Velike Lašče, southern Slovenia Rupe pri Selu, a former village in Jarčja Dolina, Municipality of Žiri, northwestern Slovenia
People: Rupe (surname) Rupe (given name) Rupe, the pen name of cartoonist Robert Baldwin
See also Rupe, Rupe, an 1899 work by Paul Gauguin - see Two Tahitian Women