Tissier is a surname of French origin. Notable people with the surname include:

Amandine Tissier (born 1993), a handball player Bernard Tissier de Mallerais (born 1945), a French Traditionalist Roman Catholic bishop Christian Tissier (born 1951), aikido teacher Georgette Tissier (1910–1959), actor and spouse of Jean Tissier Jean Tissier (1896–1973), actor and spouse of Georgette Tissier Jean-Baptiste-Ange Tissier (1814–1876), French painter Joseph Tissier, bishop of Châlons in France Luke Le Tissier (born 1996), cricketer Marcel Tissier (1903–1982), French racing cyclist Matt Le Tissier (born 1968), former football player and television presenter Maya Le Tissier (born 2002), English professional footballer Patrick Tissier (born 1952), French serial killer and rapist Pierre Tissier (1903–1955), French resistance fighter René Tissier (1899–1982), French racing cyclist