PLP may refer to:

Science and technology

Computing Packet Layer Protocol, a network-layer protocol PL/P, a programming language Physical Layer Pipe (PLPs), specified in the DVB-T2 and ATSC 3.0 broadcasting standards

Other uses in science and technology Papain-like protease, a family of cysteine protease enzymes Phantom limb pain, pain felt as from a missing limb Proteolipid protein 1 or proteolipid protein 2, associated with Pelizaeus-Merzbacher disease Pyridoxal phosphate, a coenzyme, the active form of vitamin B6

Politics People's Liberation Party (disambiguation), several political parties Parliamentary Labour Party, a group of British Labour MPs Party for Freedom and Progress, a Belgian liberal political party (1961–1992) People's Life Party, a Japanese political party Pragati Legislature Party, a 1970s political party in Orissa, India Progressive Labour Party (disambiguation), several political parties Progressive Liberal Party, a Bahamian political party

Other uses Premier League Productions PLP Architecture, a London, UK firm Pamantasan ng Lungsod ng Pasig, a university in the Philippines Peace Love & Pitbulls, a Swedish industrial rock band Phoenix Living Poets, Chatto & Windus 1960-1983 books Prosopographisches Lexikon der Palaiologenzeit, a German-language late Byzantine Empire dictionary