Mailloux is a surname. Notable people with the surname include:
Barry J. Mailloux (died 1982), Canadian computer scientist, editor and professor Cyprien O. Mailloux (1857–1932), Canadian-born American electrical engineer and inventor Élie Mailloux (1830–1893), Canadian politician Élodie Mailloux (1865–1937), Canadian nun and nursing school administrator Eugene Mailloux (1878–1929), Canadian businessman Pierre Mailloux (born 1949), Canadian psychiatrist and radio host Raymond Mailloux (1918–1995), Canadian politician
See also Mailloux River, a tributary of the north shore of the St. Lawrence River, in La Malbaie, Charlevoix-Est Regional County Municipality, Capitale-Nationale, Quebec, Canada Mailloux, a term used by Saint Pierre and Miquelon Islanders to refer to expatriates from Metropolitan France