McGrew is a surname, and may refer to:
James McGrew (1813–1910), American politician, merchant, banker and hospital director John McGrew (circa 1910 – 1999), American animator, painter and musician Lance McGrew, American NASCAR crew chief Larry McGrew (1957–2004), retired American football linebacker Reggie McGrew (born 1976), American football defensive tackle Sam McGrew (born 1984), former American football linebacker