Spike may refer to any of the following fictional characters:
Dogs Spike (Peanuts), Snoopy's brother Spike and Tyke (characters), Tom's nemesis in the cartoon series Tom and Jerry Spike the Bulldog, a character in the Warner Bros. Looney Tunes and Merrie Melodies series of cartoons Spike (Rugrats), Tommy's adoptive dog from Nickelodeon's Rugrats Spike, Heathcliff's nemesis in the comic strip and animated series Heathcliff Spike, a dog in the My Little Pony: Equestria Girls media franchise
Video game enemies Spike, a main playable character in the Ape Escape video game series Spike (Mario), a recurring enemy in the Mario games, debuting in Super Mario Bros. 3 Foreman Spike, an enemy in the NES video game Wrecking Crew Spike, a boss enemy in the video game Spyro: Year of the Dragon
Dragons One of three dragons featured in the My Little Pony animated television franchise: Spike (generation 1), a lavender dragon in the original My Little Pony series Spike (generation 3), a blue dragon who first appeared in My Little Pony: The Princess Promenade Spike (generation 4), a purple and green dragon in My Little Pony: Friendship Is Magic
Other Spike, Ace Ventura's monkey Spike, an anthropomorphic Triceratops in Extreme Dinosaurs Spike (Dinosaurs), a character in the Dinosaurs TV series Spike, alien pet of Roger Wilco in the video game Space Quest V: The Next Mutation Spike, a porcupine from the movie Over the Hedge Spike, a female robot in Jeanette Winterson's 2007 novel The Stone Gods Spike, a fairy in Disney’s Secret of the Wings Spike the Bee, a character in Disney's Donald Duck cartoons Spike, a character in the 1944 movie Million Dollar Kid Spike, a character in the 1996 American superhero movie Barb Wire Spike (Buffy the Vampire Slayer), a vampire in the TV series Buffy the Vampire Slayer and Angel Spike, Fonzie's cousin in Happy Days Spike, a character in the 28 Days Later (film series) Spike Fumo, the main character of Spike of Bensonhurst Christine "Spike" Nelson, a recurring character in the Degrassi franchise Spike Thomson, in Press Gang Spike Lester, on the soap opera Passions Spike (Marvel Comics), several Marvel Comics characters with the name Spike Freeman, another character in Marvel Comics' X-Statix/X-Force 'Spike' (a.k.a. 'Butch'), town bully in the Nancy strip and comix "Spike" Stoker, a supporting character from Jasper Fforde's Thursday Next books Joshua "Spike" Cohen, a Jew from Tom Robbins' novel Skinny Legs and All Cecil "Spike" Wilson, in the DC Comics comic book Sugar and Spike Spike Witwicky, a human from The Transformers cartoon Spike Lavery, on the soap opera All My Children Father Spike, a high-church parish priest who is mentioned in CS Lewis' book The Screwtape Letters Spike (Hollyoaks), in the UK soap opera Spike (Dragon Ball) or Akkuman, in the Dragon Ball manga series Michelangelo "Spike" Scarlatti, in the Canadian series Flashpoint Spike Spiegel, from the Japanese anime Cowboy Bebop Spike the cactus, a playable character in the video game Brawl Stars
See also Spyke, an X-Men: Evolution character