Spike the Bulldog may refer to:
Spike the Bulldog (mascot), the official mascot of Gonzaga University Spike Bulldog, an English Bulldog from the Tom and Jerry film series Spike the Bulldog (Warner Brothers), a gray bulldog who wears a red sweater and a brown bowler hat who appears in the Warner Brothers Looney Tunes and Merrie Melodies series of cartoons Spike, later renamed Butch, a character from Tex Avery's cartoons