Dumaine and DuMaine are surnames. Notable people with either surname include:
Bernard Dumaine (born 1953), French artist Cyrille Dumaine (1897–1946), Canadian politician Frederic C. Dumaine Jr. (1902–1997), American business executive Pierre DuMaine (1931–2019), American Roman Catholic bishop
Fictional characters: Dumaine, a character in Shakespeare's Love's Labour's Lost
Other uses Dumaine Street in the French Quarter of the city of New Orleans, USA.